Accuracy of Motor Performance Perception in Multiple Sclerosis

Summary

The aim of this study is to characterize perceptive abilities in PwMS compared to controls when performing prolonged functional tasks such as walking and repeated standing from a seated position. This study proposes primary and secondary research questions which will be tested in the context of two different newly designed experimental tasks and will be performed in maximum three days. The self-reported beliefs over perceptive abilities and the performance in the experimental perceptive tasks will be compared between persons with multiple sclerosis and an equally sized group of age and gender matched healthy controls. The results of this study may uncover specific deficits in the MS population and will help in defining subgroups of patients with weaker perceptive capacities to gauge their motor performance and therefore in need for tailored interventions additional to the standard practice.

Eligibility

Inclusion Criteria:

* age between 18 and 70 years old
* ability to walk for 6 minutes without rest and without the need of a walking aid
* ability to repeatedly perform the sit to stand transitions on a standard chair (43cm seat height) without hand support

For People with Multiple Sclerosis group

* a diagnosis of MS (2017 revisions of the McDonalds criteria)
* no disease relapses \>1 month preceding the start of the study

Exclusion Criteria:

* cognitive impairment hindering understanding of study instructions
* ongoing or suspected pregnancy
* musculoskeletal disorders in the lower limbs
* cardiovascular red flags for exercise (screened with Physical Activity Readines Questionnaire)
* other diagnosis for neurological or metabolic disease limiting the full execution of the tests

Conditions1

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