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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RECRUITINGPhase 3Sponsored by Hoffmann-La Roche
Actively Recruiting
PhasePhase 3
SponsorHoffmann-La Roche
Started2025-07-02
Est. completion2035-07-31
Eligibility
Age50 Years – 90 Years
Healthy vol.Accepted
Locations68 sites

Summary

This study is a pre-screening process used to assess participants' potential eligibility for Roche interventional Alzheimer's disease studies.

Eligibility

Age: 50 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* Ability and willingness to participate in an interventional clinical study, including meeting key eligibility criteria of linked interventional Roche AD studies (e.g., specific age ranges)
* Ability and willingness to receive information about potential eligibility in an associated interventional Roche AD study

Exclusion Criteria:

* Dependency in basic activities of daily living (bADLs) due to cognitive impairment
* Visual or auditory impairment that would prevent them from performing the cognitive assessments (eyeglasses and hearing aids are permitted)
* Any self-reported evidence or known diagnosis of a neurological or neurodegenerative condition that may lead to cognitive impairment other than AD
* History of severe, clinically significant central nervous system trauma
* Any serious medical condition that precludes a participant's safe participation and completion of a clinical study
* For participants with a clinical diagnosis of MCI or mild AD: Previous AD diagnosis based on biomarker confirmation with an approved or validated rule in method (e.g., amyloid PET or cerebrospinal fluid, blood biomarker) is exclusionary

Conditions2

Alzheimer's DiseaseAlzheimers Disease

Locations68 sites

University of Alabama at Birmingham
Birmingham, Alabama, 35233
Banner Alzheimer?s Institute
Banner Sun Health Research Institute
Sun City, Arizona, 85351
Sun Valley Research Center, Inc.
Imperial, California, 92251
Inglewood Clinicals
Inglewood, California, 90301

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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