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Cancer and Immune Cell Metabolism in Patients With Hematological Malignancies

RECRUITINGSponsored by University Hospital, Basel, Switzerland
Actively Recruiting
SponsorUniversity Hospital, Basel, Switzerland
Started2025-10-29
Est. completion2035-12
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

This study investigates how metabolism in cancer and immune cells shapes the bone marrow environment, influences therapy resistance, and affects outcomes in hematological malignancies.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* age \> 18 years,
* signed written informed consent
* For participants with hematological cancers: diagnosis of MDS, AML, ALL, PMF or post-ET/PV MF

Exclusion Criteria:

* pregnant or lactating women,
* inability to give consent,
* active malignant disease (other than MDS, AML, ALL, PMF or post-ET/PV MF in the last 3 - years prior to study inclusion).
* For healthy donors: previous or current hematological disease, previous or current other malignant disease,

Conditions2

CancerHematologic Malignancy

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