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Meloxicam in Mohs Micrographic Surgery

RECRUITINGPhase 4Sponsored by University of Oklahoma
Actively Recruiting
PhasePhase 4
SponsorUniversity of Oklahoma
Started2025-10-15
Est. completion2026-06-02
Eligibility
Age18 Years – 110 Years
Healthy vol.Accepted
Locations1 site

Summary

The goal of this clinical trial is to explore alternative methods of postoperative pain control in Mohs micrographic surgery. The main aims are: * To provide more information to the Mohs surgery community regarding postoperative pain control. * Reducing pain improves the overall comfort and well-being of patients, leading to a better post-operative experience. * To provide patients with an alternative and potentially superior NSAID for pain control (compared to standard-of-care ibuprofen). Researchers will compare 1) a single of dose Meloxicam 7.5 mg, followed by acetaminophen 500 mg; 2) a single dose of Meloxicam 15 mg, followed by acetaminophen 500 mg; 3) a single dose of acetaminophen 500 mg, followed by alternating ibuprofen 200 mg and acetaminophen 500 mg to see which better moderate pain control and patient satisfaction. Participants will be asked to complete pain and patient satisfaction surveys.

Eligibility

Age: 18 Years – 110 YearsHealthy volunteers accepted
Inclusion Criteria:

* All adult patients who consents to the study and are undergoing Mohs micrographic surgery at the University of Oklahoma.

Exclusion Criteria:

* Women who are pregnant, suspected to be pregnant, or planning to become pregnant during the study period will be excluded from participation.
* Chronic liver disease (chronic hepatitis, acute hepatitis, cirrhosis, NASH, NAFLD, alcoholic liver disease, hemochromatosis, Wilson's disease)
* Chronic kidney disease stage III or greater,
* Aspirin-sensitive asthma
* History of chronic NSAID use
* Patients vulnerable to drug interactions
* GI bleeds
* Peptic ulcers
* Non-English speakers

Conditions3

CancerPostoperative Pain, AcuteSkin Cancer

Locations1 site

University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
Chase Pitchford405-271-6110Chase-Pitchford@ouhsc.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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