Additional Effects of Neural Mobilization on Pain, Balance and Quality of Life in Diabetic Neuropathy

Summary

Diabetic Peripheral Neuropathy (DPN) is a common complication of diabetes, affecting up to 50% of patients and causing pain, numbness, and balance impairments, which increase the risk of falls, ulcers, and reduced quality of life. Current treatments mainly manage symptoms, highlighting the need for adjunctive approaches. This randomized controlled trial will evaluate the additional effects of Neural Mobilization (NM) on pain, balance, and quality of life in DPN. Thirty-two patients with type 2 diabetes and DPN will be recruited at Fauji Foundation Hospital and screened using the Michigan Neuropathy Screening Instrument (MNSI). Participants will be randomized into two groups: (1) NM plus Balance Training with standard care and (2) Balance Training alone, each for six weeks (two 30-minute sessions/week). Pain will be assessed using the Numeric Pain Rating Scale (NPRS), balance using the Berg Balance Scale, and quality of life using the Norfolk QOL-DN questionnaire. Outcome measures will be recorded at baseline and post-intervention. Ethical approval will be obtained from FUMC ERC, and data will be analyzed using SPSS v.22.

Eligibility

Inclusion Criteria:

* Both genders.
* Diagnosed cases of Diabetic Peripheral Neuropathy
* Age 50-75 years.
* Patients having history of type 2 Diabetes for at least 5 years.
* Presence of neuropathic symptoms (pain, numbness, tingling, balance issues).
* Patient having mild to moderate pain according to NPRS

Exclusion Criteria:

* Patients with Neurological Disorders like Stroke, multiple sclerosis, Parkinson's disease.
* Chronic Pain Conditions or Conditions unrelated to DPN (e.g., fibromyalgia, osteoarthritis).
* Foot Ulcers/Infection: Active ulcers or infections on lower limbs.
* Uncontrolled Diabetes
* Severe Balance Impairment Individuals unable to perform basic balance tests (e.g., unable to stand unaided for a few seconds).

Conditions4

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