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Home-Based Strategies for Knee Osteoarthritis

RECRUITINGN/ASponsored by Istanbul University - Cerrahpasa
Actively Recruiting
PhaseN/A
SponsorIstanbul University - Cerrahpasa
Started2025-10-09
Est. completion2025-12-01
Eligibility
Age40 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07212647

Summary

Knee osteoarthritis (KOA) is a common chronic joint condition leading to pain, functional limitations, and reduced quality of life. This randomized controlled trial aims to evaluate and compare the effectiveness of a structured home-based exercise program versus topical diclofenac sodium therapy in improving pain, functional outcomes, and health-related quality of life among adults with early-stage KOA. The results are intended to provide evidence on the optimal components of home-based conservative management strategies.

Eligibility

Age: 40 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adults aged 40-70 years
* Diagnosed with Kellgren-Lawrence grade I-II knee osteoarthritis
* Ability to provide written informed consent

Exclusion Criteria:

* Advanced KOA (Kellgren-Lawrence grade IV) requiring arthroplasty
* Prior knee surgery within the past year
* Intra-articular injections within the last 3 months
* Neurological, rheumatological, or systemic conditions affecting mobility
* Inability to comply with study procedures

Conditions3

ArthritisKnee OsteoarthritisKnee Osteoarthritis (Knee OA)

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