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Using E-Nose Technology to Track Treatment Response in People With Non-Small Cell Lung Cancer

RECRUITINGPhase 2Sponsored by Memorial Sloan Kettering Cancer Center
Actively Recruiting
PhasePhase 2
SponsorMemorial Sloan Kettering Cancer Center
Started2025-10-10
Est. completion2027-10
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations7 sites

Summary

The researchers are doing this study to test the ability of a new technology called breathprinting, or electronic nose (E-Nose), to measure changes in certain chemicals in the breath before and after standard neoadjuvant therapy in people with NSCLC.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age ≥18
* Untreated clinical stage I NSCLC amenable to upfront surgery
* Untreated stage II to IIIB NSCLC amenable to neoadjuvant treatment followed by surgery
* ECOG Performance Status of ≤2 Of note, the E-nose is a completely noninvasive technology (only breath samples are collected). Therefore, this intervention would have no effects on a developing human fetus. There are therefore no requirements for the study population related to contraception or pregnancy testing.

Conditions3

CancerLung CancerNon Small Cell Lung Cancer

Locations7 sites

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)
Basking Ridge, New Jersey, 07920
Gaetano Rocco, MD212-639-3478
Memorial Sloan Kettering Monmouth (All Protocol Activities)
Middletown, New Jersey, 07748
Gaetano Rocco, MD212-639-3478
Memorial Sloan Kettering Bergen (All Protocol Activities)
Montvale, New Jersey, 07645
Gaetano Rocco, MD212-639-3478
Memorial Sloan Kettering Suffolk-Commack (All Protocol Activities)
Commack, New York, 11725
Gaetano Rocco, MD212-639-3478
Memorial Sloan Kettering Westchester (All Protocol Activities)
Harrison, New York, 10604
Gaetano Rocco, MD212-639-3478

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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