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Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA

RECRUITINGSponsored by City of Hope Medical Center
Actively Recruiting
SponsorCity of Hope Medical Center
Started2025-01-15
Est. completion2026-06-18
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT07224789

Summary

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Adults (≥18 years old)
* Histologically confirmed colorectal cancer (Stage I-III)
* Availability of pre-treatment plasma samples
* Written informed consent provided

Exclusion Criteria:

* History of other active malignancies within the past 5 years
* Poor sample quality or hemolysis
* Inability to provide informed consent

Conditions2

CancerColorectal Cancer

Locations1 site

City of Hope Medical Center
Duarte, California, 91016
Ajay Goel, PhD626-218-3452ajgoel@coh.org

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