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Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules

RECRUITINGSponsored by M.D. Anderson Cancer Center
Actively Recruiting
SponsorM.D. Anderson Cancer Center
Started2025-11-14
Est. completion2028-08-31
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →

NCT07226804

Summary

To observe the outcomes of nsPFA therapy to treat benign thyroid nodules.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Eligibility Criteria

* Scheduled to undergo ultrasound guided nsPFA as standard of care
* Age 18 to 80 years.
* Capable of providing independent consent.
* Presence of biopsy-confirmed benign thyroid nodule , defined as one of the following:

  * Benign FNA X 2 or
  * Benign US guided FNA X 1 + benign thyroid nodule ultrasound appearance (TI-RADS 2) or
  * Benign FNA X 1 and radiographic/laboratory evidence of functional nature
* Nodule measuring \>2cm in greatest dimension
* Presence of compressive symptoms reasonably attributable to thyroid nodule (i.e. pressure sensation, dysphagia, dysphonia, respiratory distress)
* No abnormal cervical lymph nodes during screening visit .

Exclusion Criteria

* Age \<18
* Patients considered unsuitable for nsPFA by the treating physician

Conditions3

CancerPulsed Field AblationThyroid Nodules

Locations1 site

MD Anderson Cancer Center
Houston, Texas, 77030
Victoria E Banuchi, MD346-217-8668vebanuchi@mdanderson.org

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