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Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative Diseases

RECRUITINGSponsored by Ospedale Policlinico San Martino
Actively Recruiting
SponsorOspedale Policlinico San Martino
Started2025-02-28
Est. completion2034-09-17
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07235111

Summary

The study aims to use 'omics' sciences, employing the most advanced technologies currently available, in order to identify pathogenic genomic variants, proteins and/or altered molecular pathways in neurodegenerative diseases and to obtain a new and more complete characterisation of subjects affected by the neurodegenerative diseases under study. Thanks to the integration of genomic, gene expression (transcriptomic and epigenomic), protein and metabolic data and clinical data, the study also aims to identify new markers for the diagnosis, prognosis, also in terms of response to therapy, and monitoring of neurodegenerative diseases. The study involves the enrolment of at least 1.200 individuals with neurodegenerative disease.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria

• Patients suffering from neurodegenerative diseases

Exclusion Criteria

• Patients not suffering from neurodegenerative diseases

Conditions7

ALS (Amyotrophic Lateral Sclerosis)Alzheimer DiseaseAlzheimer's DiseaseFTDMCIParkinson DiseaseYoung-onset Dementia

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