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TIVA Versus Balanced Anesthesia on Muscle Mass in CRC Surgery

RECRUITINGN/ASponsored by Grigore T. Popa University of Medicine and Pharmacy
Actively Recruiting
PhaseN/A
SponsorGrigore T. Popa University of Medicine and Pharmacy
Started2025-09-20
Est. completion2026-02
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07237438

Summary

This study is aimed at clarifying changes in body composition during the perioperative period and identifying risk factors for skeletal muscle mass loss in patients with colorectal cancer. The investigators will asess the impact of the type of anaesthesia (total intravenous anaesthesia/sevoflurane anaesthesia) for colorectal surgery on the muscle function and mass, which will be evaluated using ultrasound, dynamometry and bioimpedance.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

• adult patients diagnosed with colorectal cancer and scheduled for open colorectal surgery at the Regional Institute of Oncology, Iaşi, Romania

Exclusion Criteria:

* lack the capacity to consent
* extremity amputation
* paraplegia
* diseases affecting the muscles (such as stroke, lower-limb immobilization from a plaster, neurodegenerative diseases, peripheral neuropathy or muscle dystrophy)
* terminal cancer

Conditions3

CancerColorectal Cancer (CRC)Sarcopenia

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