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DEXDES Trial: Dexmedetomidine-Desflurane Combination in Laparoscopic Colectomy

RECRUITINGN/ASponsored by Tam Anh Research Institute
Actively Recruiting
PhaseN/A
SponsorTam Anh Research Institute
Started2025-12-01
Est. completion2026-12-31
Eligibility
Age18 Years – 65 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07239479

Summary

This randomized double-blind controlled clinical trial aims to evaluate the efficacy and safety of combining Dexmedetomidine with Desflurane in patients undergoing elective laparoscopic colectomy. The study will assess whether the combination can reduce Desflurane consumption, improve intraoperative hemodynamic stability, and enhance postoperative recovery compared to Desflurane alone.

Eligibility

Age: 18 Years – 65 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age 18-65 years
* ASA Physical Status I-II
* Elective laparoscopic colectomy
* Written informed consent provided

Exclusion Criteria:

* Severe cardiac, hepatic, or renal disease
* COPD or bronchial asthma
* Chronic opioid or psychotropic medication use
* Atrioventricular block (grade II-III), sick sinus syndrome
* Significant intraoperative bleeding or hemodynamic instability

Conditions2

CancerColorectal Neoplasms

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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