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Virtual Reality Exposure Therapy for Obsessive-Compulsive Disorder: A Randomized Controlled Trial in Inpatients

RECRUITINGN/ASponsored by National Institute of Mental Health, Czech Republic
Actively Recruiting
PhaseN/A
SponsorNational Institute of Mental Health, Czech Republic
Started2022-11-15
Est. completion2026-12-30
Eligibility
Age17 Years – 55 Years
Healthy vol.Accepted

Summary

The aim of this study is to evaluate the efficacy of virtual reality exposure therapy (VRET) as a treatment for obsessive-compulsive disorder (OCD). Participants are randomly assigned to one of the following interventions: a) exposure condition - the group with a standard CBT program enriched with exposure therapy in VR (VRET), b) control condition 1 - the group with a standard CBT program enriched with VR cognitive training aimed at cognitive flexibility or c) control condition 2 - standard CBT program without any additional VR intervention. The treatment effect will be evaluated using pre/post assessments, as well as monitoring adherence to exposure and response prevention assignments.

Eligibility

Age: 17 Years – 55 YearsHealthy volunteers accepted
Inclusion Criteria:

* Diagnosis of OCD (F42) using currently valid DSM-V and ICD-11
* Fluent in Czech

Exclusion Criteria:

* Any other psychiatric, neurological and serious somatic illness
* Substance abuse
* Psychotropic medication (e.g. benzodiazepines) except antidepressants, antipsychotic medication and hypnotics.
* Contradictions to using a virtual reality (e.g., epilepsy, balance problems)
* Pregnancy
* Cardiostimulator and mental implants

Conditions5

AnxietyCognitive Behavior TherapyObsessive-compulsive DisorderVirtual Reality Cognitive TrainingVirtual Reality Exposure Therapy

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