Evaluation of Three Tests to Assess Social Cognition in Huntington Disease

Summary

The goal of this observational study is to learn about the usefulness of a test of social functioning in persons with Huntington disease. Huntington disease affects motor function, psychological well-being and cognitive functions ("thinking abilities" such as paying attention, remembering and solving problems). It is also believed to affect important social functions, including the ability to understand others' intentions and emotions (social cognition). The test of interest in this study is called The Double Movie for the Assessment of Social Cognition-Multiple Choice (DMASC-MC) and will be compared to two other similar and well-known tests. The main question which the study aims to answer is: • Is DMASC-MC a useful tool for detecting problems with social functioning in adult persons with early Huntington disease? In the study, participants will meet with a medical doctor and a psychologist for assessment of different symptoms related to Huntington disease, including social functioning. Better methods for identifying problems with social functioning could help persons with Huntington disease and their families in mainly two ways. Firstly, it could increase their understanding of how the disease has affected them. Secondly, a better understanding of these problems could lead to better recommendations and interventions from medical teams, which would also benefit persons with Huntington disease and families.

Eligibility

Inclusion Criteria:

Inclusion criteria for persons with HD

1. Clinical diagnosis of HD
2. CAG repeat: 40 and more

Inclusion criteria for control group

1\. No heritage of HD or negative pre-symptomatic HD gene test

Exclusion Criteria:

Participants in both groups are excluded from the study if any of the following criteria apply:

1. Dementia or MOCA\<19, The Mini Mental State Examination (MMSE) \<19
2. Other neurological disorders
3. Ongoing psychosis
4. Ongoing alcohol/drug addiction
5. Other native language than Swedish
6. Severe problems with vision and hearing

Conditions2

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