Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus

Summary

The study aims at defining the role of ferroptosis s in the physiopathology of systemic lupus erythematosus (SLE). Ferroptosis (phenomenon of cellular death regulated by iron) is a metabolic pathway potentially implicated in SLE with potential for the discovery of new therapeutic strategies.

Eligibility

Inclusion Criteria:

* age ≥ 18 years;
* diagnosis of systemic lupus erythematosus;
* being affiliated to health insurance, willing to participate and to sign informed consent;
* control group : patients with a diagnosis of rheumatoid arthritis or an inflammatory bowel disease.

Exclusion Criteria:

* pregnant or breastfeeding women;
* patient concerned by articles L 1121-5 to L 1121-8 (persons deprived of their liberty by a judicial or administrative decision, minors, persons of legal age who are the object of a legal protection measure or unable to express their consent).

Conditions2

Interventions1

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