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Combined Subcostal and Lateral Transversus Abdominis Plane Block for Postoperative Analgesia Versus Thoracic Epidural Analgesia in Patients Undergoing Major Abdominal Cancer Surgery

RECRUITINGN/ASponsored by Assiut University
Actively Recruiting
PhaseN/A
SponsorAssiut University
Started2025-12-10
Est. completion2026-04-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07273136

Summary

This study aims to evaluate the safety and efficacy of combined subcostal and lateral transversus abdominis plane (TAP) for postoperative analgesia versus thoracic epidural anesthesia (TEA) in patients undergoing major abdominal cancer surgery.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiologists (ASA) physical status I-III.
* Scheduled for major abdominal surgeries including: (e.g., gastrectomy, colectomy, hepatectomy, cystectomy, total abdominal hysterectomy, Nephrectomy, pancreatectomy).

Exclusion Criteria:

* Intraoperative hemodynamic instability.
* History or evidence of coagulopathy.
* Infection or abdominal wall masses at injection site.
* Morbid obesity.
* Other Medical conditions including mental illness or substance abuse.
* Known allergy to local anesthetics.
* Chronic opioid use or chronic pain conditions.
* Pregnancy.

Conditions7

CancerLateralMajor Abdominal Cancer SurgeryPostoperative AnalgesiaSubcostalThoracic Epidural AnalgesiaTransversus Abdominis Plane Block

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