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AF Screening in Patients With Abnormal Echocardiographic Parameters

RECRUITINGN/ASponsored by Tze-Fan Chao
Actively Recruiting
PhaseN/A
SponsorTze-Fan Chao
Started2025-03-17
Est. completion2031-12-31
Eligibility
Age20 Years+
Healthy vol.Accepted

Summary

To evaluate the feasibility of specific echocardiographic parameters as criteria for AF screening and to determine the AF detection yield of scheduled extended ECG monitoring compared to contemporary care.

Eligibility

Age: 20 Years+Healthy volunteers accepted
Inclusion Criteria: patients who met any of the following criteria

1. LAE: defined as LAD ≥ 45 mm or LAVI \> 34 ml/m2;
2. LVH: defined as LV septal or posterior wall thickness ≥ 15 mm;
3. E/e' \> 14;
4. grade II or III diastolic dysfunction;
5. VHD;
6. HF: defined as LVEF \< 40% or LVEF ≥40% with clinical presentation compatible with Framingham criteria, New York Heart Association functional classification II-IV, and N-terminal pro-B type natriuretic peptide (NT-proBNP) \> 125 pg/ml.

Exclusion Criteria:

* Patients with a history of AF or atrial flutter, congenital heart disease, acute coronary syndrome undergoing urgent percutaneous coronary intervention within 3 months, uncontrolled hyperthyroidism, end-stage renal disease, unstable hemodynamic status or any known major comorbidities or medical conditions with expected life expectancy less than 1 year are excluded.

Conditions2

Atrial Fibrillation (AF)Heart Disease

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