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Prognostic Values of Coronary Microvascular Dysfunction in Patients With Dilated Cardiomyopathy

RECRUITINGSponsored by Second Affiliated Hospital, School of Medicine, Zhejiang University
Actively Recruiting
SponsorSecond Affiliated Hospital, School of Medicine, Zhejiang University
Started2026-01-06
Est. completion2027-11-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07293338

Summary

The goal of this observational study is to learn about the long-term prognostic of coronary microvascular dysfuction in Patients with Dilated Cardiomyopathy. The main question it aims to answer is: Does the coronary microvascular dysfunction impact the outcomes in Patients with Dilated Cardiomyopathy.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Dilated cardiomyopathy comfirmed by echocardiography: LVDd \> 55 mm in men or \> 50 mm in women.
* Clinically evident congestive heart failure: Compatible symptoms and signs, and BNP ≥ 35 pg/mL or NT-proBNP ≥ 125 pg/mL, and LV systolic dysfunction defined by LVEF \< 45 %.
* Coronary angiography showing stenosis ≤ 50 % in all major epicardial vessels.

Exclusion Criteria:

* Patients with coronary artery disease, hypertensive heart disease, rheumatic valvular heart disease, myocarditis, and other secondary cardiomyopathies.
* poor angiographic image quality

Conditions2

Dilated Cardiomyopathy (DCM)Heart Disease

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