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A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus

RECRUITINGPhase 1Sponsored by Eli Lilly and Company
Actively Recruiting
PhasePhase 1
SponsorEli Lilly and Company
Started2026-01-14
Est. completion2026-10
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07299084

Summary

The purpose of this study is to evaluate how fasting and stopping the use of tirzepatide affects the amount of food and drink that stays in the stomach after a meal. Ultrasound will be used to check the stomach content after a test meal.

Eligibility

Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria:

* Meet one of the following criteria:

  * Have type 2 diabetes
  * Have obesity
  * Have overweight with at least one health issue related to weight but without type 2 diabetes

Exclusion Criteria:

* Have a condition that affects how their stomach empties
* Have had weight loss surgery
* Have type 1 diabetes
* Have any major medical conditions or histories that could interfere with the study

Conditions4

DiabetesDiabetes Mellitus, Type 2ObesityOverweight

Interventions1

Tirzepatide

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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