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A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
NOT_RECRUITINGPhase 1Sponsored by Eli Lilly and Company
No longer actively recruiting
PhasePhase 1
SponsorEli Lilly and Company
Started2026-01-14
Est. completion2026-11
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT07299084
Summary
The purpose of this study is to evaluate how fasting and stopping the use of tirzepatide affects the amount of food and drink that stays in the stomach after a meal. Ultrasound will be used to check the stomach content after a test meal.
Eligibility
Age: 18 Years – 70 YearsHealthy volunteers accepted
Inclusion Criteria: * Meet one of the following criteria: * Have type 2 diabetes * Have obesity * Have overweight with at least one health issue related to weight but without type 2 diabetes Exclusion Criteria: * Have a condition that affects how their stomach empties * Have had weight loss surgery * Have type 1 diabetes * Have any major medical conditions or histories that could interfere with the study
Conditions4
DiabetesDiabetes Mellitus, Type 2ObesityOverweight
Interventions1
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No longer actively recruiting
PhasePhase 1
SponsorEli Lilly and Company
Started2026-01-14
Est. completion2026-11
Eligibility
Age18 Years – 70 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →
NCT07299084