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Virtual Lesion Segmentation and Mandibular Ameloblastoma Radiographic Safety Margin

RECRUITINGN/ASponsored by Alexandria University
Actively Recruiting
PhaseN/A
SponsorAlexandria University
Started2025-01-01
Est. completion2026-12-01
Eligibility
Healthy vol.Accepted

Summary

Reconstruction of segmental mandibular defects is in a continuous state of evolution utilizing the recent advances in Computer-Aided Designing (CAD) and preoperative Virtual Surgical Planning (VSP). The anterior iliac crest is one of the ideal reservoirs for autogenous harvesting of a bi-cortical bone block with 1:1 cortical to cancellous bone ratio which is optimal for rapid and predictable consolidation. The aim of this study is the utility of VSP guided by CT and confirmation by histopathological analysis in achieving negative margins and preventing recurrence of mandibular ameloblastoma.

Eligibility

Healthy volunteers accepted
Inclusion Criteria:

1. Patients with histologically confirmed ameloblastoma using a preoperative biopsy.
2. Patients with ameloblastoma that require segmental mandibular continuity defect, not involving the condyle.

Exclusion Criteria

1. Patients with lateral segmental mandibular defect involving the condyle.
2. Patients with an active infection at the site of resection.
3. Patients with recurrent lesion after resection.

Conditions2

AmeloblastomaCancer

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