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The Ultrasonographic Evaluation of Abdominal Accessory Respiratory Muscle Thickness in Patients With Parkinson's Disease: Correlation With Disease Severity and Expiratory Respiratory Muscle Strength

RECRUITINGSponsored by Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Actively Recruiting
SponsorIstanbul Physical Medicine Rehabilitation Training and Research Hospital
Started2025-12-29
Est. completion2026-02-28
Eligibility
Age18 Years – 75 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07308795

Summary

Parkinson's disease is a neurodegenerative disorder characterized by both motor and non-motor symptoms. The involvement of respiratory muscles can lead to impairments in respiratory function in these patients. In this study is to evaluate the thickness of abdominal accessory respiratory muscles using ultrasonography in patients with Parkinson's disease. Additionally, the relationship between disease severity and expiratory respiratory muscle strength will be examined. The study will include Parkinson's patients at different stages of the disease, with respiratory muscle thickness measured via ultrasonography. The collected data will then be compared with disease severity and expiratory muscle strength.

Eligibility

Age: 18 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria:

* Age \> 18 years
* Parkinson's disease diagnosis with Modified Hoehn and Yahr stages 1-2-3
* Mini-Mental State Examination (MMSE) score \> 23
* Body Mass Index (BMI) \< 30

Exclusion Criteria:

* Active smokers
* Individuals with a diagnosis of active chest disease
* Those with hemodynamic instability
* Individuals with unstable vital signs
* Parkinson's patients who cannot be controlled with medical treatment
* Parkinson Plus syndromes

Conditions5

Abdominal Accessory Respiratory Muscle ThicknessMaximum Expiratory PressureMaximum Inspiratory PressureParkinson Disease (PD)Parkinson's Disease

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