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Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology

RECRUITINGSponsored by Centre Hospitalier Universitaire, Amiens
Actively Recruiting
SponsorCentre Hospitalier Universitaire, Amiens
Started2025-12-17
Est. completion2027-01
Eligibility
Age18 Years – 47 Years
Healthy vol.Accepted

Summary

Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity. Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment. However, few studies have analyzed the long-term reproductive outcomes of these interventions, nor how patients ultimately use or do not use the FP options once in remission. This project aims to better understand the effectiveness, utilization, and psychological impacts of these strategies. This work is part of an effort to understand and evaluate fertility preservation practices implemented for women of reproductive age undergoing cancer treatment at the Amiens-Picardie University Hospital (CHU). Its objective is to document patient pathways, clinical decisions, techniques employed, and reproductive outcomes observed after remission, in order to identify potential areas for improvement in the support and follow-up of these patients, thereby enhancing the overall quality and coordination of care. This work is conducted alongside the development of a fertility observatory at the Department of Medicine and Reproductive Biology, CHU Amiens-Picardie.

Eligibility

Age: 18 Years – 47 YearsHealthy volunteers accepted
Inclusion Criteria:

* Women
* Aged between 18 and 47 years
* Diagnosed with cancer or hematological disorders requiring potentially gonadotoxic treatment
* Having undergone a medical fertility preservation consultation
* Followed at Amiens Picardie University Hospital (CHU Amiens Picardie) in the department of Reproductive Medicine
* Currently in remission
* Having expressed non-opposition to participation in the study

Exclusion Criteria:

* Absence of remission
* Patients deprived of liberty by administrative or judicial decision, or placed under legal protection (guardianship or curators)
* Decline to participate in the study

Conditions14

Assisted Reproductive TechnologyCancerCancer RemissionFemale Cancer SurvivorsFertility CounselingFertility ObservatoryFertility PreservationFertility Preservation TechniquesLive Birth RateOncology

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