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The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

RECRUITINGSponsored by Brigham and Women's Hospital
Actively Recruiting
SponsorBrigham and Women's Hospital
Started2024-09-04
Est. completion2028-03-04
Eligibility
Age35 Years – 79 Years
Healthy vol.Accepted
Locations3 sites
View on ClinicalTrials.gov →

NCT07315997

Summary

Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.

Eligibility

Age: 35 Years – 79 YearsHealthy volunteers accepted
Inclusion Criteria:

* RA diagnosed by a rheumatologist
* Age 40- 79
* ≥1 ASCVD risk factor including prediabetes, hypertension, BMI \>30, current or history of cigarette smoking

Exclusion Criteria:

* Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
* Patients with diabetes mellitus
* Pregnancy

Conditions4

ArthritisAtherosclerotic Cardiovascular Disease (ASCVD)Heart DiseaseRheumatoid Arthritis (RA

Locations3 sites

Massachusetts General Hospital: Rheumatology
Boston, Massachusetts, 02114
Sheila Arvikar, MD6177267938sarvikar@mgh.harvard.edu
Brigham and Womens Hospital
Boston, Massachusetts, 02115
Katherine P Liao, MD, MPH617-525-8819kliao@bwh.harvard.edu
Brigham and Women's Faulkner Hospital
Boston, Massachusetts, 02130
Nicole Yang, MD6179837720nyang2@bwh.harvard.edu

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Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

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