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Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant Depression

RECRUITINGN/ASponsored by Charles University, Czech Republic
Actively Recruiting
PhaseN/A
SponsorCharles University, Czech Republic
Started2026-01-05
Est. completion2028-01-05
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The RTMSECT2 study was design to compare the application of electroconvulsive therapy augmented by transcranial magnetic stimulation. Subject will be compared both within groups and in group using psychometric scales and different deliver energy

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age equal to 18 or higher
* MADRS (Montgomery-Asberg Depression Scale) qual or higher than 20
* Major depressive disorder according to ICD 10

Exclusion Criteria:

* Other axis 1 disorder (for example schizofrenia, addiction, etc.)
* No dementia
* ECT in the last 3 months
* TMS in the last 3 months
* Psychotic disease or symptoms
* Ppregnancy or lactation
* Any neurological disease (for example epilepsy, etc.)
* Participation in another clinical trial within the last 30 days
* somatic condition which contraindicates ECT

Conditions3

DepressionMajor Depressive Disorder (MDD)Treatment Resistant Depression (TRD)

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