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Correlation Between Advanced Glycation End Products and Gastric Motility Disorder in Diabetes Gastroparesis

RECRUITINGSponsored by Northern Jiangsu People's Hospital
Actively Recruiting
SponsorNorthern Jiangsu People's Hospital
Started2026-01-07
Est. completion2027-05-31
Eligibility
Age18 Years – 75 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07324785

Summary

This study is a prospective observational study. The study will explore the correlation between advanced glycation end products and gastric motility disorder in diabetic gastroparesis（DGP) through the collection of blood and gastric tissue samples and relevant data of patients with DGP and control group patients without diabetes history and gastroparesis symptoms.

Eligibility

Age: 18 Years – 75 YearsHealthy volunteers accepted
Inclusion Criteria for diabetes gastroparesis group:

* Meet the diagnostic criteria for diabetes
* Presence of symptoms (see assessment of Gastroparesis Cardinal Symptom Index)
* Age range from 18 to 75 years old
* Voluntarily participate and sign an informed consent form

Inclusion Criteria for control group:

* No history of diabetes
* No symptoms (see assessment of Gastroparesis Cardinal Symptom Index)
* Age range from 18 to 75 years old
* Voluntarily participate and sign an informed consent form

Exclusion Criteria for diabetes gastroparesis group and control group:

* Currently taking prokinetic drugs, anticholinergic drugs, and dopamine drugs that may affect gastric motility
* Has a history of gastrointestinal surgery
* Pregnant or preparing to conceive
* There are neurological disorders such as Parkinson's disease that affect gastrointestinal function
* Outlet obstruction caused by organic lesions in the pylorus

Conditions2

DiabetesDiabetic Gastroparesis

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