Study of Platelet Population Changes Under Circulatory Support With ECMO

Summary

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

Eligibility

Inclusion Criteria:

* Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital.
* Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.

Exclusion Criteria:

* Subject who has expressed their opposition to participating in the study.
* Subject under legal protection.
* Subject under guardianship or curatorship.

Conditions3

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