Does Ultrasound Guidance Axillary Incision Improve Sentinel Lymph Node Detection in Breast Cancer?

Summary

This single-center randomized controlled trial evaluates whether detecting the first lymph node at the axillary entrance with ultrasound guidance, followed by a targeted axillary incision over the pencil-marked projection, improves sentinel lymph node identification compared to the conventional axillary hairline landmark. The study hypothesizes that this technique enables a smaller incision, minimizes tissue dissection, and reduces operative time.

Eligibility

Inclusion Criteria:

* \* Patients with clinical stage T1-T3 disease (tumor ≤5 cm), pN0-pN1 (one to three regional lymph nodes with micrometastases or metastases), and M0 (no distant metastasis) are eligible. Post-neoadjuvant yT1-T3, yN0-yN1, and M0 status are also eligible. All patients are undergoing axillary staging.
* Clinically negative axilla
* Written informed consent must be obtained prior to inclusio

Exclusion Criteria:

* Younger than 18 years
* Previous breast malignancy
* Pregnancy
* Pre-operative diagnosis of axillary lymph node metastases
* The presence of multiple clinically involved or suspicious lymph nodes
* Unable or unwilling to provide informed consent.

Conditions4

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