Dual-energy CT vs. MRI in the Evaluation of Squamous Cell Carcinomas of the Oral Cavity and Oropharynx

Summary

The diagnostic and pre-therapeutic assessment of squamous cell carcinomas requires a neck and chest CT scan and a neck and facial MRI, which is the most effective examination, to establish the TNM stage of the tumor. However, obtaining this complete assessment can delay treatment. Confirmation of the non-inferiority of 40keV dual-energy CT in BOLT compared to MRI would spare the patient an additional MRI examination, speed up the pre-treatment assessment, reduce the loss of opportunity due to delayed treatment, and free up MRI imaging slots, which are still insufficient in the region.

Eligibility

Inclusion Criteria:

* Adult patient (≥18 years)
* presenting with oral or oropharyngeal squamous cell carcinoma proven by histopathological analysis of a biopsy
* having undergone a clinical examination with nasofibroscopy by an ENT surgeon specializing in cancer surgery
* a contrast-enhanced cervicofacial MRI
* and a contrast-enhanced cervicofacial DECT with BOLT maneuver.

Exclusion Criteria:

* A lesion other than oral or oropharyngeal squamous cell carcinoma
* A labial location
* A contraindication to performing one or both of the imaging examinations.

Conditions3

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