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Sleep and Circadian Interventions for College Students at High Risk of Suicide

RECRUITINGN/ASponsored by University of Pittsburgh
Actively Recruiting
PhaseN/A
SponsorUniversity of Pittsburgh
Started2026-06-18
Est. completion2029-03
Eligibility
Age18 Years – 25 Years
Healthy vol.Accepted
Locations1 site

Summary

The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide risk among high risk young adults. Investigators will evaluate three interventions targeting sleep in acutely suicidal college students enrolled in intensive outpatient treatment. Participants will be randomly assigned to one of three intervention groups: 1. Triple Chronotherapy (TCT)+ Transdiagnostic Sleep and Circadian Intervention (TSC) 2. Transdiagnostic Sleep and Circadian Intervention (TSC) 3. Sleep Feedback (SF) Participants will be followed for 6 months with primary outcome domains of suicidal thoughts and behaviors and depression evaluated by blinded clinicians at short (Days 1-4 of intervention), medium (2 months) and long (6 month) term intervals.

Eligibility

Age: 18 Years – 25 YearsHealthy volunteers accepted
Inclusion Criteria:

* Enrolled or planning to enroll in treatment at COSTAR Intensive Outpatient Program
* English language fluency and literacy sufficient to engage in study protocol
* Suicidal ideation or suicide attempt in past month
* Clinically significant sleep disturbance, operationalized as Pittsburgh Sleep Quality Index global PSQI score \>= 7, and/or delayed bedtimes (\>midnight), and/or \>2 hours in sleep timing variability

Exclusion Criteria:

* Non-affective psychosis per electronic health record (EHR) review and/or baseline clinical assessment, or symptom severity or psychosocial functioning impairments that preclude participation
* Contraindications for either sleep deprivation or bright light therapy (e.g., bipolar disorder; seizure disorder; photosensitizing medication)
* Intellectual disability precluding comprehension of study procedures
* Evidence of untreated obstructive sleep apnea and/or restless legs syndrome
* Life-threatening medical condition requiring immediate treatment (such as cancer; end stage disease)
* Pregnancy

Conditions4

DepressionSleepSleep DisturbanceSuicide

Locations1 site

Western Psychiatric Hospital/University of Pittsburgh
Pittsburgh, Pennsylvania, 15213
Dawn Rice, MS412-297-1947ricedm@upmc.edu

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