Scalp Hair Metabolomics in Severe Obesity

Summary

The purpose of this research study is to investigate how body weight and weight-loss surgery affect the natural chemicals found in scalp hair over time. We will also find out how common and severe hair thinning/hair loss and muscle loss are in the first 6 months after bariatric surgery.

Eligibility

Inclusion Criteria:

All subjects:

1. Age 21-70 years
2. Ability to provide informed consent

Healthy weight controls:

1. BMI of 18.5-24.9 kg/m2
2. No chronic disease
3. No long-term medications

Severe obesity:

1. BMI of \> 32.5 kg/m2
2. Scheduled to undergo bariatric surgery

Exclusion Criteria:

1. Pregnancy
2. Any factors likely to limit adherence to study protocol
3. Any history of autoimmune or scarring alopecia (eg. alopecia areata, discoid lupus, lichen planopilaris)

Conditions5

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