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Dynamic Airway Resistance & ML: Guide Sputum Suction in Ventilated Patients

RECRUITINGN/ASponsored by Affiliated Hospital of Nantong University
Actively Recruiting
PhaseN/A
SponsorAffiliated Hospital of Nantong University
Started2025-10-30
Est. completion2028-12-30
Eligibility
Age18 Years – 90 Years
Healthy vol.Accepted

Summary

Research has shown that timely suctioning not only improves survival rates but also enhances the quality of life in ventilator-dependent patients. However, clinical judgment on the optimal timing for suctioning currently relies primarily on physician experience, lacking scientific evidence \[10\]. Airway viscous resistance reflects the frictional resistance encountered by gas flow within the airways and is closely associated with airway patency. When airway secretions increase, viscous resistance undergoes dynamic changes. Therefore, analyzing these dynamic variations in viscous resistance derived from ventilator waveforms to determine the optimal suctioning timing and assess its clinical impact on the progression of pulmonary inflammation holds significant scientific value and offers new insights and methodologies for clinical practice.

Eligibility

Age: 18 Years – 90 YearsHealthy volunteers accepted
Inclusion Criteria:

* Clinical diagnosis of Acute Respiratory Distress Syndrome (ARDS)
* Clinical diagnosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
* Clinical diagnosis of Severe pneumonia

Exclusion Criteria:

* Clinical diagnosis of multiple organ failure;
* Clinical diagnosis of multiple organ bleeding;

Conditions4

DepressionMechanical Ventilation Pressure HighRespiratory Depression NeonatalVentilator-Associated Pneumonia (VAP)

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