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Decoupling Immunotherapy Toxicity and Cancer Response
RECRUITINGSponsored by M.D. Anderson Cancer Center
Actively Recruiting
SponsorM.D. Anderson Cancer Center
Started2026-01-09
Est. completion2028-06-30
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →
NCT07382752
Summary
This study is a novel evaluation of cardiotoxicity after ICI therapy based on traditional CV risk factors with the addition of metabolomic profiles, epigenetic aging, and CHIP. It is not an extension of previous work in ICI therapy.
Eligibility
Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria: 1. Age ≥ 18 years 2. Plan to start immune checkpoint inhibitor for cancer therapy Exclusion Criteria: 1. No baseline blood collection prior to initiation 2. At time of evaluation not determined to be a good candidate for evaluation of outcome events by the principal investigator
Conditions3
CancerCardiovascularTumor
Locations1 site
The University of Texas M. D. Anderson Cancer Center
Houston, Texas, 77030
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Actively Recruiting
SponsorM.D. Anderson Cancer Center
Started2026-01-09
Est. completion2028-06-30
Eligibility
Age18 Years+
Healthy vol.Accepted
Locations1 site
View on ClinicalTrials.gov →
NCT07382752