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Role of Exercise in PRISm

RECRUITINGN/ASponsored by The University of Hong Kong
Actively Recruiting
PhaseN/A
SponsorThe University of Hong Kong
Started2025-07-14
Est. completion2027-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07387432

Summary

Preserved Ratio Impaired Spirometry (PRISm) describes individual with spirometry findings of forced expiratory volume (FEV1) and forced vital capacity (FVC) ratio greater than 0.7 but with the FEV1 less than 80% predicted. While the spirometry findings of individuals with PRISm can be transited into obstructive pattern, remains at PRISm or become normal spirometry, limited evidence is on the role of exercise in the course of PRISm. This study aims to investigate the role of exercise, namely exercise with telehealth and walking exercise, together with smoking cessation advice, would alter the clinical course of PRISm.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* Age 18 or above
* Smoker/ ex-smoker
* Spirometry shows PRISm, with FEV1/FVC \>= 0.7 and FEV1 \<80% predicted
* Ambulatory to walk
* Able to give informed consent

Exclusion Criteria:

* Age below 18
* Non-smoker
* Spirometry does not show PRISm/ unable to perform spirometry
* Requires assistance for walking
* Umable to give informed consent

Conditions2

COPDPreserved Ratio Impaired Spirometry (PRISM)

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