Assessment of Exercise Capacity, Muscle Oxygenation and Aortic Stiffness in Patients With Mitral Stenosis

Summary

Heart valve diseases are the most common cause of mortality and morbidity after coronary artery disease, hypertension, and heart failure. In patients with mitral stenosis, the narrowed valve restricts blood flow, causing symptoms such as shortness of breath, fatigue, exertional dyspnea, orthopnea, and paroxysmal nocturnal dyspnea. These patients may experience decreased exercise capacity and physical activity levels, deterioration in quality of life, and deterioration in respiratory function. When reviewing the literature, we see that the study groups evaluating these factors are generally not homogeneous, and most studies conducted in patients with mitral stenosis evaluate patients who have undergone percutaneous mitral balloon valvuloplasty.

Eligibility

Inclusion Criteria:

Patients;

* Between the ages of 18-80
* Patients who have undergone mitral valve intervention due to mitral stenosis
* At least 3 months have passed since the intervention

Healthy controls;

* Between the ages of 18 and 80
* Agreeing to participate voluntarily in the study

Exclusion Criteria:

Patients;

* Patients who have undergone aortic valve intervention other than mitral valve intervention
* Acute infection
* Orthopedic, neurological or psychological disorders that will affect functional capacity

Healthy Controls;

* diagnosed chronic disease,
* acute infection
* A smoking history of at least 10 packs×years or more

Conditions2

Browse More Trials