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" TREX1 Gene Mutations and Their Role in Systemic Lupus Erythematosus

RECRUITINGSponsored by South Valley University
Actively Recruiting
SponsorSouth Valley University
Started2025-06-10
Est. completion2026-06-01
Eligibility
Age18 Years – 60 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07397728

Summary

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by diverse clinical manifestations, prominently involving the skin.

Eligibility

Age: 18 Years – 60 YearsHealthy volunteers accepted
Inclusion Criteria:

* Adult aged 18-60 years
* Diagnosed as SLE per 2019 EULAR/ACR classification criteria.
* Presence of at least one cutaneous manifestation (acute, subacute, or chronic).
* Willing to provide written informed consent for participation and genetic testing

Exclusion Criteria:

* Overlap autoimmune syndromes (e.g., dermatomyositis, systemic sclerosis).
* Systemic infection, malignancy, or pregnancy.
* Use of biologic therapy or immunosuppressive pulses within one month.

Conditions2

LupusSystemic Lupus Erythematosus

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