Multimodal Training Effects in Middle-Aged and Older Adults With Diabetic Sarcopenia

Summary

This study aims to investigate the effects of a 12-week multimodal exercise intervention on middle-aged and older adults (aged 45\~85 years) with Type 2 Diabetes Mellitus (T2DM). The program combines supervised training, home-based sessions, and digital support to improve muscle function, physical performance, metabolic control, and quality of life.

Eligibility

Inclusion Criteria:

* Diagnosed with both Type 2 Diabetes Mellitus (T2DM) and sarcopenia.
* Maintained on a stable regimen of oral hypoglycemic agents.
* Aged 45 years or older.
* Capable of communicating effectively in Mandarin or Taiwanese.
* Willing to provide informed consent or have it obtained from a legally authorized representative.

Exclusion Criteria:

* • Limited limb or joint function that prevents exercise (e.g., recent fractures or dislocations).

  * Communication barriers or severe emotional/psychological issues (e.g., uncontrolled depression or severe mental illness).
  * Severe cognitive impairment (e.g., dementia).
  * End-stage renal disease (ESRD).
  * Major comorbidities or complications, including active diabetic foot ulcers, amputation, recent myocardial infarction, severe autonomic neuropathy, or a history of stroke within the last 3 years.

Conditions3

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