Effect of Vagus Nerve Stimulation on Pain Intensity, Nerve Conduction Studies and Functional Outcomes in Diabetic Peripheral Neuropathy Patients

Summary

To evaluate the efficacy of vagus nerve stimulation in reducing neuropathic pain, symptom severity, electrophysiological studies and functional outcomes in patients with diabetic peripheral neuropathy.

Eligibility

Inclusion Criteria

* Thirty patients diagnosed with diabetic neuropathy of both genders.
* Age range between 45 and 60 years.
* Presence of numbness and/or pain in the feet with no other identifiable cause.
* Pain characterized as stabbing, electric shock-like, or burning in nature.
* Presence of glove-stocking sensory changes and abnormal sensations in the distal lower limbs.
* Ability to ambulate independently without assistance.
* Patients under full medical control.
* Hemoglobin A1c levels ranging from 6.5% to 7%.
* History of diabetes mellitus for more than 5 years.

Exclusion Criteria

* Implantation of cardiac pacemakers or other electrical stimulation devices.
* Presence of sinus bradycardia, sick sinus syndrome, or other cardiac arrhythmias.
* Lumbar radiculopathy.
* Psychiatric or mental disorders or history of seizures.
* Visual or auditory impairments or tremors affecting balance.
* Presence of other neuromuscular disorders.
* Foot deformities or active foot ulcers.
* History of lower limb surgical operations.

Conditions3

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