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Navigation Intervention for Adolescent and Young Adult Cancer Survivors

RECRUITINGN/ASponsored by Kaiser Permanente
Actively Recruiting
PhaseN/A
SponsorKaiser Permanente
Started2026-03-15
Est. completion2027-06
Eligibility
Age21 Years – 45 Years
Healthy vol.Accepted
Locations1 site

Summary

The investigators propose to: 1) Adapt an evidence-based cancer-focused patient navigation (PN) program for the Adolescent and Young Adult (AYA) cancer survivor population; and 2) Plan and conduct an effectiveness-implementation trial of this program within Kaiser Permanente Southern California (KPSC). PLEASE NOTE: This study is awarded in two phases. The UG3 phase has been awarded for the first two years; upon successful completion of this phase by meeting pre-defined milestones, the National Cancer Institute (NCI) will provide funding for the second phase of the study (Years 3-6), which will allow our team to conduct a trial to determine the effectiveness of the implementation of the adapted PN program for the AYA cancer survivor population. This application is focused on the initial UG3 phase and will update the protocol for the UH3 trial upon successful completion of the UG3 milestones and receipt of the UH3 award. The primary objectives in the UG3 phase of the study are to adapt and tailor an existing PN program to meet the needs of AYA cancer survivors and the local clinical context via (a) interviews with key stakeholders (patients, clinicians, administrators) and (b) guidance from our AYA Primary Care Survivorship Council. The investigators will conduct a pilot study of the adapted PN program and refine the program to enhance acceptability to patients and clinicians, enhance feasibility and effectiveness, and develop and pilot evaluation tools and methods prior to the start of the UH3 phase of the trial, which will be a larger trial. Objectives will be updated for the UH3 phase once awarded.

Eligibility

Age: 21 Years – 45 YearsHealthy volunteers accepted
Inclusion Criteria:

* Received diagnosis of local or regional breast, ovarian, cervical, testicular, colon/rectal, melanoma, endometrial, sarcoma, or thyroid cancer between the ages of 15-39 years ("index cancer")
* Current age 21-45 years
* Diagnosed and treated for index cancer within Kaiser Permanente Southern California adult medical oncology and/or surgery
* Current Kaiser Permanente insurance coverage

Exclusion Criteria:

* Patients with a history of or current diagnosis of leukemia or lymphoma
* Patients with metastatic disease at diagnosis

Conditions10

Breast CancerCancerCervical CancerColon Rectal CancerEndometrial CancerMelanoma (Skin Cancer)Ovarian CancerSarcomaTesticular CancerThyroid Cancer

Locations1 site

KP Southern California - Department of Research & Evaluation
Pasadena, California, 91101

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