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Cardiac Remodelling Following Endovascular Repair of the Aorta

RECRUITINGSponsored by Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Actively Recruiting
SponsorLisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
Started2025-09-01
Est. completion2026-09-01
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07415447

Summary

To assess the effects of endovascular aortic repair on cardiac morphology and function

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

\- Patients over 18-year-old, with degenerative arch, descending thoracic or abdominal aortic aneurysms, penetrating aortic ulcers or intramural hematomas managed with total EVAR in elective setting.

Exclusion Criteria:

* Heart failure with an ejection fraction \<35 vs 50% or New York Heart Association (NYHA) class III and IV.
* LV wall motion abnormality.
* Moderate to severe valve disease.
* History of (or expected within the study period) cardiac/aortic surgery.
* Coronary artery disease.
* Atrial fibrillation.
* Congenital heart disease.
* Connective tissue disorders.
* Chronic kidney disease (eGFR \<30 mL/min/173 m2).
* Moderate to severe pulmonary disease as indicate either by post bronchodilator FEV1 (%predicted) \<50% or Modified Medical Research Council Dyspnoea Scale (mMRC) 3-4.
* CMR contraindications (non-compatible pacemakers and metal implants, and claustrophobia).

Conditions3

Aortic DiseaseCardiac FailureHeart Disease

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