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Bone Regeneration Using PRF After Cyst Enucleation

RECRUITINGN/ASponsored by Sana'a University
Actively Recruiting
PhaseN/A
SponsorSana'a University
Started2025-05-19
Est. completion2026-04-19
Eligibility
Age18 Years – 80 Years
Healthy vol.Accepted

Summary

This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws. The study will assess bone healing outcomes and compare PRF application with conventional management methods.

Eligibility

Age: 18 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients diagnosed with odontogenic cysts requiring surgical enucleation.
* Presence of a postoperative osseous defect in the jaws after cyst enucleation.
* Age ≥ 18 years.
* Systemically healthy patients (ASA I or II).
* Patients willing to participate and sign informed consent.

Exclusion Criteria:

* Patients with systemic diseases affecting bone healing (e.g., uncontrolled diabetes, osteoporosis).
* Patients receiving bisphosphonates or long-term corticosteroid therapy.
* Smokers (\>10 cigarettes/day).
* Pregnant or lactating women.
* Patients with acute infection at the surgical site.
* Patients unwilling to participate or unable to attend follow-up visits.

Conditions4

CancerJaw CystsOdontogenic CystOsseous Defect After Cyst Enucleation

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