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Adapting RDAD for DS

RECRUITINGN/ASponsored by University of Kansas Medical Center
Actively Recruiting
PhaseN/A
SponsorUniversity of Kansas Medical Center
Started2026-03-31
Est. completion2026-07-31
Eligibility
Healthy vol.Accepted
Locations1 site

Summary

The goal of this clinical trial is to observe feasibility and initial efficacy of a remotely delivered exercise and dementia caregiving intervention in older adults with Down syndrome and their caregivers.

Eligibility

Healthy volunteers accepted
Inclusion Criteria - Adults with Down syndrome:

* Age \>35 yrs. with a diagnosis of DS as self-reported or reported by caregiver. This age range was selected as cognitive decline related to AD is observed at age \~31 in adults with DS.
* Sufficient functional ability to understand directions, communicate preferences, wants, and needs through spoken language.
* Living at home or in a supported living environment with a parent/caregiver who agrees to serve as a study partner.
* Self-reported ability to participate in physical activity.

Exclusion Criteria - Adults with Down syndrome:

* Unable to participate in moderate-to-vigorous physical activity.
* Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.

Inclusion Criteria - Caregivers

* Age ≥18 yrs.
* Reports being a primary caregiver of an adult with DS.
* English speaking.
* Self-reported ability to participate in physical activity.

Exclusion Criteria - Caregivers

* Unable to participate in moderate PA, i.e., brisk walking.
* Self-reported, cardiovascular, metabolic or renal disease and/or signs or symptoms.

Conditions3

Alzheimer's DiseaseAlzheimer's Disease (AD)Down Syndrome (DS)

Locations1 site

University of Kansas Medical Center
Kansas City, Kansas, 66160
Amy Bodde, PhD913-574-2447abodde@kumc.edu

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