|

Effect of Mediterranean vs Paleolithic Diet on RA Activity, Sarcopenia and QOL: 12-Week RCT

RECRUITINGN/ASponsored by Kasr El Aini Hospital
Actively Recruiting
PhaseN/A
SponsorKasr El Aini Hospital
Started2026-01-17
Est. completion2026-06-15
Eligibility
Age40 Years – 60 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07438652

Summary

This study aims to evaluate the effects of Mediterranean and Paleolithic dietary interventions on nutritional status, disease activity, fatigue, sleep, and quality of life in adults with rheumatoid arthritis (RA). Participants aged 40-60 years will be randomly assigned to follow either a Mediterranean diet, a Paleolithic diet, or continue their usual diet for 12 weeks. The study will assess anthropometric measurements, disease activity score (DAS28), laboratory biomarkers (CBC, CRP, ESR, lipid profile, fasting glucose, HbA1c), and patient-reported outcomes. The trial will determine whether these diets improve RA management and overall well-being.

Eligibility

Age: 40 Years – 60 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients classified as having rheumatoid arthritis according to the 2010 rheumatoid arthritis ACR/ EULAR classification criteria with a selected age group of 40 to 60 years old.

Exclusion Criteria:

* Patients with comorbidities (e.g., diabetes mellitus, hypertension, gout, thyroid dysfunction).

Conditions2

ArthritisRheumatoid Arthritis (RA

Browse More Trials

Arthritis trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.