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Measuring Fluid Buildup in Cancer Patients

RECRUITINGSponsored by Jens Rikardt Andersen
Actively Recruiting
SponsorJens Rikardt Andersen
Started2026-02-01
Est. completion2026-07-31
Eligibility
Age18 Years+
Healthy vol.Accepted

Summary

The goal of this study is to improve the monitoring of fluid retention in cancer patients. The main question it aims to answer is: Can segmental bioelectrical impedance analysis be used to monitor local fluid retention (edema) in cancer patients? We will include: * Breast cancer patients with fluid and or lymph retention in one or both arms after radiotherapy (outpatients) * Cancer patients with fluid retention in one or both legs after chemotherapy (hospitalized) Participants will: * Have measurements taken using bioelectrical impedance * Provide blood samples and 24-hour urine collection * Weight monitorering * Complete diet and fluid registration (inclusive enteral and parenteral) * Have clinical palpatory and measurement assessment of oedema.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria (Outpatient breast cancer patients with lymphoedema after radiotherapy):

* Habile
* Must be able to speak and read Danish
* Has received/is receiving radiotherapy due to breast cancer within the last 6 months
* Is being followed in the Oncology Outpatient Clinic at Aalborg University Hospital
* Age ≥ 18 years
* Visible lymphoedema in at least one upper extremity

Inclusion Criteria (Hospitalized cancer patients with peripheral oedema in one or both lower extremities after chemotherapy):

* Habile
* Must be able to speak and read Danish
* Has received/is receiving chemotherapy due to cancer within the last 2 months
* Hospitalised in the Oncology Ward at Aalborg University Hospital
* Estimated length of hospital stay of at least 6 days
* Age ≥ 18 years
* Visible peripheral oedema in at least one lower extremity

Exclusion Criteria (both groups):

* Pregnant or breastfeeding women
* Amputated limb(s)
* Pacemaker or implanted cardioverter-defibrillator due to risk of interference from the electrical signal
* Metallic prostheses due to risk of interference with the device signal
* Inability to lie still for the duration of the measurement interval (minimum 2 minutes at a time)
* Inability to stand on a scale, i.e. permanently bedridden.
* Inability to cooperate with urine collection
* Receiving dialysis
* Terminal illness

Conditions7

Bioelectrical ImpedanceCancerChemotherapyFluid BalanceLymphoedemaOedemaRadiotherapy

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