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Effect of Striatal Temporal Interference Stimulation on Language Processing in Neurodegenerative Diseases

RECRUITINGN/ASponsored by Masaryk University
Actively Recruiting
PhaseN/A
SponsorMasaryk University
Started2026-03
Est. completion2027-12
Eligibility
Age60 Years – 80 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07449117

Summary

The purpose of this study is to investigate the immediate effects of non-invasive temporal interference stimulation (TIS) targeting the striatum on sentence processing and brain connectivity in patients with neurodegenerative diseases.

Eligibility

Age: 60 Years – 80 YearsHealthy volunteers accepted
Inclusion Criteria:

* Possible or probable Mild Cognitive Impairment with Lewy Bodies (MCI-LB), in Parkinson's Disease (MCI-PD) or Amnestic Mild Cognitive Impairment (aMCI).

Exclusion Criteria:

* Any severe psychiatric disorder.
* History of other neurological diseases affecting the central nervous system.
* Severe head trauma.
* Uncompensated internal or oncological disease.
* Presence of MRI-incompatible metal in the body (e.g., pacemaker).

Conditions4

Lewy Body Disease With Mild Cognitive ImpairmentMild Cognitive Impairment (MCI) AmnesticParkinson's DiseaseParkinson's Disease With Mild Cognitive Impairment

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