|

SII Levels Following iPACK Block With Adductor Canal Block in Knee Arthroplasty

RECRUITINGN/ASponsored by Poznan University of Medical Sciences
Actively Recruiting
PhaseN/A
SponsorPoznan University of Medical Sciences
Started2026-03-01
Est. completion2026-05-31
Eligibility
Age65 Years – 100 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07449442

Summary

This randomized controlled trial evaluates the effect of ultrasound-guided iPACK block with Adductor Canal Block (ACB) on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal anesthesia. SII, calculated as platelet × neutrophil / lymphocyte count, is used as a composite marker of perioperative inflammatory and immune response. The study investigates whether iPACK block with ACB attenuates the systemic inflammatory reaction to surgical trauma compared to sham block.

Eligibility

Age: 65 Years – 100 YearsHealthy volunteers accepted
Inclusion Criteria:

* Patients with ASA classification I-III
* Aged 65-100 years
* Who will be scheduled for hip arthroplasty under spinal anesthesia

Exclusion Criteria:

* Patients who have a history of bleeding diathesis
* Take anticoagulant therapy
* History of chronic pain before surgery
* Multiple trauma
* patients unable to assess their pain (dementia)
* patients operated under general anesthesia
* patients having an infection in the region of the procedure
* the patient who does not accept the procedure

Conditions2

ArthritisKnee Osteoarthritis

Interventions2

Ropivacaine HydroclorideSodium chloride

Related trials

Browse More Trials

Arthritis trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.