|

Effect of Different Concentrations of Sevoflurane for Anesthesia Induction in Pediatric Ophthalmic Surgery

RECRUITINGN/ASponsored by Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Actively Recruiting
PhaseN/A
SponsorJoint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Started2025-02-25
Est. completion2026-02-25
Eligibility
Age1 Year – 6 Years
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07450495

Summary

This randomized controlled trial aims to compare the effectiveness and safety of 6% versus 8% sevoflurane inhalation induction in pediatric patients undergoing minor ophthalmic surgery. The primary outcome is emergence agitation assessed using the Pediatric Anesthesia Emergence Delirium (PAED) scale. Secondary outcomes include hemodynamic parameters, induction time, recovery time, and adverse events.

Eligibility

Age: 1 Year – 6 YearsHealthy volunteers accepted
Inclusion Criteria:

* Children aged 1 to 6 years (12-72 months)
* Scheduled to undergo minor ophthalmic surgery (e.g., chalazion excision) under general anesthesia
* American Society of Anesthesiologists (ASA) physical status I
* Assessed as suitable for inhalation anesthesia by anesthesiologists
* Written informed consent obtained from parents or legal guardians

Exclusion Criteria:

* ASA physical status II or higher
* Known hepatic or renal dysfunction
* Congenital heart disease
* History of malignant hyperthermia
* Known allergy to sevoflurane
* History of asthma or severe respiratory disease
* Upper respiratory tract infection within the past 4 weeks
* Anticipated difficult airway
* Refusal of participation by parents or legal guardians

Conditions2

CancerChalazion

Interventions1

Sevoflurane

Browse More Trials

Cancer trials

Trial data from ClinicalTrials.gov. Trial status and eligibility can change — verify directly with the study contact or on ClinicalTrials.gov.

This site does not provide medical advice. Always consult your doctor before considering enrollment in a clinical trial. Learn more on our About page.