Facility-Based Multi-Modal Rehab vs. Home-Based Resistance Exercise for Quality of Life in Breast Cancer Survivors

Summary

This study evaluates the comparative effectiveness of a multi-modal facility-based rehabilitation program (therapist-led resistance exercise and relaxation training) versus a self-directed home-based resistance exercise program in post-treatment breast cancer survivors. Participants in both intervention groups will complete a 16-week program consisting of two exercise sessions per week.The multimodal, therapist-led approach is hypothesized to result in superior improvements in physical performance and quality of life outcomes compared to self-directed home exercise

Eligibility

Inclusion Criteria:

* Histologically confirmed primary breast cancer
* Stage I-III non-metastatic breast cancer following lumpectomy or mastectomy
* Completed adjuvant chemotherapy (with or without radiotherapy)
* Age ≥ 18 years
* Able to understand and follow the study protocol
* Willingness to attend facility-based exercise training.

Exclusion Criteria:

* Metastatic (Stage IV) breast cancer
* Morbid obesity (BMI \> 40 kg/m²)
* Uncontrolled hypertension (systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 99 mmHg)
* Presence of implantable medical devices (e.g., pacemakers, nerve stimulators)
* Presence of metallic surgical implants (e.g., total hip or knee replacements) that interfere with assessment devices
* Contraindications for resistance training (e.g., acute infectious disease, severe cardiac disease, severe respiratory insufficiency)
* Concurrent malignant diseases
* Current participation in intense systematic exercise training (defined as at least 1 hour, twice per week)
* Previous participation in an exercise intervention clinical trial.

Conditions4

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