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Expression of SLC25A48 in Chronic Obstructive Pulmonary Disease

RECRUITINGSponsored by Fu Jen Catholic University
Actively Recruiting
SponsorFu Jen Catholic University
Started2026-06-29
Est. completion2026-12-31
Eligibility
Age18 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07474220

Summary

This study aims to investigate the expression level of SLC25A48, a mitochondrial choline transporter, in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease, and to analyze its correlation with inflammatory markers and choline metabolic byproducts.

Eligibility

Age: 18 Years+Healthy volunteers accepted
Inclusion Criteria:

* pre-COPD or COPD stages I-IV as per the 2023 GOLD guidelines (case group)
* healthy individuals without chronic diseases or major medical conditions

Exclusion Criteria:

* diagnosed with neuromuscular diseases
* experienced respiratory disease exacerbation requiring emergency care or hospitalization in the past three months
* assessed by a physician to have severe malnutrition or a significantly low BMI
* continuously taking folic acid supplements
* willing to receive or have already received self-paid nutrition clinic services at this hospital

Conditions2

COPDChronic Obstructive Pulmonary Disease

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