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Brief Title: Aerobic Training on Cerebrovascular Function, Cognition and Gait in Parkinson's Disease

RECRUITINGN/ASponsored by Raphael Mendes Ritti Dias
Actively Recruiting
PhaseN/A
SponsorRaphael Mendes Ritti Dias
Started2026-02-28
Est. completion2027-06-30
Eligibility
Age40 Years+
Healthy vol.Accepted
View on ClinicalTrials.gov →

NCT07478146

Summary

This randomized controlled trial will investigate the effects of a 12-week supervised aerobic training program on cerebrovascular function, peripheral vascular health, cardiovascular autonomic modulation, cognition, non-motor symptoms, sleep, mood, gait biomechanics, quality of life, and body composition in patients with Parkinson's disease (Hoehn \& Yahr stages 1-3). Participants will be randomly allocated to aerobic training or usual care.

Eligibility

Age: 40 Years+Healthy volunteers accepted
Inclusion Criteria:

* Clinical diagnosis of Parkinson's disease
* Hoehn \& Yahr stages 1-3
* Stable antiparkinsonian medication for at least 4 weeks
* Montreal Cognitive Assessment (MoCA) score ≥ 18
* Ability to walk independently (with or without assistive device)
* Medical clearance for participation in moderate-intensity exercise

Exclusion Criteria:

* Change in medication
* Contraindication to exercise

Conditions2

PARKINSON DISEASE (Disorder)Parkinson's Disease

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